FDA Approves Two New Drugs to Treat Eczema

The U.S. Food and Drug Administration approved drugs from AbbVie Inc and Pfizer Inc for treating eczema, a skin disease, the companies said on Friday.

AbbVie’s Rinvoq and Pfizer’s Cibinqo have been approved to treat moderate-to-severe atopic dermatitis, or eczema, in patients who do not respond to previous treatment or when use of other treatments is not recommended.

Rinvoq’s approval was expanded from rheumatoid arthritis to treat eczema for patients 12 years and older, while Cibinqo was approved for use in only adults.

Both the drugs belong to a class called JAK inhibitors, which block inflammation-causing enzymes known as Janus kinases and target a range of autoimmune diseases.

Both Pfizer and AbbVie cited risks of serious infections and cardiovascular events, among others.

The expanded approval for Rinvoq follows significant delays amid concerns over safety of JAK inhibitors.

Cibinqo had last year received approvals from the European and UK regulators.

The FDA last month added its strictest warning to labels of JAK inhibitor drugs from Pfizer, Eli Lilly and AbbVie following a review of Pfizer’s Xeljanz, another JAK inhibitor.

The initial results from a trial showed an increased risk of serious heart-related problems and cancer in some patients being treated with the drug. 

© 2022 Thomson/Reuters. All rights reserved.

There is no custom code to display.

Blogs

670 KBOI GUEST BLOG: Governor Brad Little

670 KBOI GUEST BLOG: Governor Brad Little

Biden’s vaccine mandate is not the solution By Governor Brad Little Americans are deeply divided on COVID-19 and the response to it. Public health has turned political, there’s no doubt about it. But the situation playing out in hospitals across the country isn’t up for debate. There are more patients in need of critical care…

670 KBOI GUEST BLOG: Governor Brad Little

670 KBOI GUEST BLOG: Governor Brad Little

670 KBOI GUEST BLOG: Governor Brad Little Idaho to help secure U.S.-Mexico border because Biden won’t July 7, 2021 Last week I announced my plan to send Idaho State Police (ISP) troopers to Arizona to help secure the United States-Mexico border and curb the flow of illegal drugs into Idaho due to failed Biden-Harris immigration…

670 KBOI GUEST BLOG: Speaker of the House Scott Bedke

670 KBOI GUEST BLOG: Speaker of the House Scott Bedke

670 KBOI GUEST BLOG: Speaker of the House Scott Bedke   Happy Birthday, Idaho – Let’s Celebrate and Maintain the Idaho Way BY: Speaker of the House Scott Bedke, Oakley There is no better place to live, work, and raise a family than Idaho. As a proud Idaho native who believes, promotes and lives our…